Z axis won't home or move down

I recently built a 3D printer using a RAMBO board and got it working with Repetier (I found this to be better than Marlin). All axes were moving normally until I adjusted the steps per mm through pronterface. Now the Z axis cannot be controlled by the LCD, and only moves up when I use pronterface. When I try to home, the motors make a really loud screeching like sound until I press the Z min endstop. The endstop isn't triggered from default though, using M119 shows that it is open until I close it as it should be. I've already tried setting an offset but that doesn't seem to work either. 
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