So if I understand you correctly Cura with 114350 lines uses 100MB in host while the 95166 lines from Slic3r utilize 2500MB in host? That would be quite drastic and a bad sign. Would that slic3r file also behave like that on the other pc? If yes it must contain something that confuses the host and I'd like to get a copy of that file so I can analyse what goes wrong. If it works on the other pc it must be some file wrong.
Visualization only depends on 3d settings stored in registry (HKCU/Software/RepetierHost) and has nothing to do with any slicer configs (Cura in work directory subfolder, slic3r wherever you wanted it normally in home/AppData/Roaming/Slic3r).
You could try reinstalling host in case a binary got corrupted somehow, but then I would expect cura gcode to behave the same.