To look at it we would need to find the reason and that is not possible without your exact setup. Many users are printing happily with this combination of software. What I think is simplify 3d creates a bit different gcode. Maybe moving a bit slower or some other minor difference. And that is enough to not trigger reset.
First step would be to watch the hosts log. After a reset the firmware writes the reset reason into log. If it is a brown out, your power unit just sag too low in voltage. This can happen if you are near the edge and enough power consumer start running the same time. Until this it might be good but if then e.g. bed joins to 3 motors you are in trouble.